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Intervertebral Disc

Disc degeneration reduces the delamination strength of the anulus fibrosus in the rabbit anular disc puncture model.
Gregory, Diane E; Bae, Won C; Sah, Robert L; Masuda, Koichi.
Spine J. 2014 Jul 1;14(7):1265-71. doi: 10.1016/j.spinee.2013.07.489. Epub 2014 Mar 2.

Progressive Disc Herniation: An Investigation of the Mechanism Using Radiologic, Histochemical, and Microscopic Dissection Techniques on a Porcine Model.
Tampier, Claudio; Drake, Janessa DM; Callaghan, Jack P; McGill, Stuart.
Spine (Phila Pa 1976). 2007 Dec 1;32(25):2869-74. doi: 10.1097/BRS.0b013e31815b64f5.

A complex interaction between Wnt signaling and TNF-α in nucleus pulposus cells.
Hiyama, Akihiko; Yokoyama, Katsuya; Nukaga, Tadashi; Sakai, Daisuke; Mochida, Joji.
Arthritis Res Ther. 2013 Nov 14;15(6):R189. doi: 10.1186/ar4379.
Abstract     Full text

Molecular Basis of Intervertebral Disc Degeneration and Herniations: What Are the Important Translational Questions?
Kadow, Tiffany; Sowa, Gwendolyn; Vo, Nam & Kang, James D
Clin Orthop Relat Res. 2015 Jun;473(6):1903-12. doi: 10.1007/s11999-014-3774-8.

The molecular basis of intervertebral disc degeneration.
Kepler, Christopher K; Ponnappan, Ravi K; Tannoury, Chadi A; Risbud, Marakand V & Anderson, David G
Spine J. 2013 Mar;13(3):318-30. doi: 10.1016/j.spinee.2012.12.003. Epub 2013 Feb 8.

Nerve growth factor expression and innervation of the painful intervertebral disc.
Freemont, A J; Watkins, A; Le Maitre, C; Baird, P; Jeziorska, M; Knight, M T N; Ross, E R S; O'Brien, J P & Hoyland, J A
J Pathol. 2002 Jul;197(3):286-92. doi: 10.1002/path.1108.

ISSLS prize winner: A study of diffusion in human lumbar discs: a serial magnetic resonance imaging study documenting the influence of the endplate on diffusion in normal and degenerate discs.
Rajasekaran, S; Babu, J Naresh; Arun, R; Armstrong, B Roy Wilson; Shetty, Ajoy Prasad & Murugan, Subramaniam
Spine (Phila Pa 1976). 2004 Dec 1;29(23):2654-67. doi: 10.1097/01.brs.0000148014.15210.64.

Intervertebral disk nutrition: a review of factors influencing concentrations of nutrients and metabolites.
Grunhagen, Thijs; Shirazi-Adl, Aboulfazl; Fairbank, Jeremy C T & Urban, Jill P G
Orthop Clin North Am. 2011 Oct;42(4):465-77, vii. doi: 10.1016/j.ocl.2011.07.010.

Lumbar disc herniation and cauda equina syndrome following spinal manipulative therapy: a review of six court decisions in Canada.
Boucher, Pierre; Robidoux, Sébastien.
J Forensic Leg Med. 2014 Feb;22:159-69. doi: 10.1016/j.jflm.2013.12.026. Epub 2014 Jan 7.

Outcomes of acute and chronic patients with magnetic resonance imaging-confirmed symptomatic lumbar disc herniations receiving high-velocity, low-amplitude, spinal manipulative therapy: a prospective observational cohort study with one-year follow-up.
Leemann, Serafin; Peterson, Cynthia K; Schmid, Christof; Anklin, Bernard & Humphreys, B Kim.
J Manipulative Physiol Ther. Mar-Apr 2014;37(3):155-63. doi: 10.1016/j.jmpt.2013.12.011. Epub 2014 Mar 11.
Abstract     Full text

Outcomes from magnetic resonance imaging-confirmed symptomatic cervical disk herniation patients treated with high-velocity, low-amplitude spinal manipulative therapy: a prospective cohort study with 3-month follow-up.
Peterson, Cynthia K; Schmid, Christof; Leemann, Serafin; Anklin, Bernard & Humphreys, B Kim.
J Manipulative Physiol Ther. 2013 Oct;36(8):461-7. doi: 10.1016/j.jmpt.2013.07.002. Epub 2013 Aug 12.

The cellular and molecular biology of the intervertebral disc: A clinician's primer.
Erwin, W Mark & Hood, Katherine E
J Can Chiropr Assoc. 2014 Sep;58(3):246-57.
Abstract     Full text

What is intervertebral disc degeneration, and what causes it?
Adams, Michael A & Roughley, Peter J
Spine (Phila Pa 1976). 2006 Aug 15;31(18):2151-61. doi: 10.1097/01.brs.0000231761.73859.2c.

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